Donegal County Council have agreed to throw financially troubled Finn Harps a potential life-line.The Ballybofey club needs to raise €48,000 by 21 December to meet certain debts in order to comply with the requirements for applying for a First Division licence for 2012.At a meeting tonight, local councillors backed an emergency motion to provide €20,000 for the club. Councillors spoke about the importance of the club to the county and said that it would be a tragedy if the club, which joined the League of Ireland in 1969, went out of senior soccer.HARPS THROWN €20,000 LIFELINE BY COUNTY COUNCIL was last modified: November 28th, 2011 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)
A Donegal Judge said that EU legislation on fishing regulation was “extremely complicated” as he passed sentence on a trawler skipper who pleaded guilty to several offences at Letterkenny Circuit Court.Letterkenny Court.Jonathan Kenny of Chestnut Grove, Viewmount, Waterford, initially pleaded not guilty to failing to facilitate an inspection by a sea fish protection body at Greencastle Pier on December 13, 2013. He had also contested a charge of fishing in an un-authorised area on a date between November 1, 2013 and December 13, 2013 and failing to have a stowage plan for Monkfish on dates between December 6 and 13.After a jury was sworn in to hear the case, Kenny asked to be re-arraigning and changed his plea on all counts.The court heard that the vessel, the Saltees Quest, was based at Dunmore East and while not owned by the defendant was being skippered by him at the time.Fisheries Officer John Hederman said the vessel had traveled up the Irish Sea to fish grounds off north Donegal and netted a haul valued at €7,000 before bad weather forced them into Greencastle harbour.While the vessel did have quota it was prohibited from fishing the area at the time as a matter of helping conserve fish stocks.The Monkfish was a “high value” fish and was required to have a written stowage plan in place in the event of an inspection by officers.He added that they sealed off the boat and when they arrived the next day the seals had been broken and they were subjected to abuse and intimidation from crew members.Barrister for the state, Patricia McLaughlin BL outlined that it was the ship masters job to control the crew during such inspections.Defence barrister, Richard Lyons SC, said his client had been fishing 17 years and skippering for eight years, without any previous convictions.He said he misinterpreted the legislation and believed he was entitled to fish “Area six” at the time and made no secret he was there.He claimed he used over 5,00 litres of fuel to get there and the catch, valued at €7,000, was a low yield just prior to Christmas and the crews frustration was brought out on the inspectors.Judge John O’Hagan said such measures were in place to help conserve fish stocks but added fishing legislation was “extremely complex”.He highlighted the dangers posed by the occupation as it contained “a lot of risk”, and noted fisheries officers also had a difficult job.The judge said a catch worth €7,000, when divided out among the crew and expenses, meant there “ain’t a lot left”. He noted his plea and previous good record and fined him €1,000 on each count as well as the value of the catch, totaling €10,000.JUDGE ADMITS FISHING LEGISLATION IS COMPLICATED AS SKIPPER PLEADS GUILTY was last modified: July 22nd, 2015 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:donegalFishingGreencastletrawler
ARCATA >> As the summer has gone on, Crabs manager Tyson Fisher and pitching coach Eric Giacone have had the luxury of looking down to the end of the dugout and know, for the most part, the relief pitcher they send down to the bullpen is going to come in and get the job done.That was once again on display Wednesday night.Led by Kevin Calderhead, the Crabs’ bullpen picked up starting pitcher Junior Davis in a big way, throwing nearly five complete innings of shutout baseball in Humboldt’s 5-1 …
(Visited 25 times, 1 visits today)FacebookTwitterPinterestSave分享0 You have built-in machinery and software that’s beyond your awareness. Here are ways to enlist your equipment for better health.Navigation: How do you know where you are? Some German scientists went looking in the brain for the equipment that keeps you from getting lost. A press release from Ruhr-Universitaet-Bochum (RUB). Here’s their tip of the day after researching with ten epileptics given a navigational task: focus, and don’t let irrelevant details distract you.“Distributed and local activity patterns appear to be related: the brain regions that contributed to distributed spatial representations also contained fairly precise information on a local scale,” explains Nikolai Axmacher. “The accuracy of spatial representations was rather variable; interestingly, more reliable representations occurred if the brain’s overall activity in a rapid frequency range was comparatively low.” These results suggest that spatial navigation is particularly successful if other, irrelevant activities can be suppressed.“Fight cancer from the inside: This tip will have to wait for years of clinical trials, but it appears you have a potent anti-cancer agent inside you. A press release from Concordia University starts with this teaser:Where can you find the next important weapon in the fight against cancer? Just do a little navel-gazing. New research from Concordia confirms that a tool for keeping the most common forms of cancer at bay could be in your gut.The molecule with “massive potential” is called lithocholic acid. It’s a bile acid produced in the liver. In tests of cancer cells in a petri dish, lithocholic acid showed the most potential to kill cancer cells of thousands of body chemicals they tested. “When entering a cancer cell, the acid goes to ‘energy factories’ called mitochondria and then sends molecular signals that lead to the cells’ demise.” Here’s another benefit the molecule may have for all of us: it appears to slow down aging, too.Save your hearing: We all know we should avoid loud noises, but perhaps you didn’t know your body is trying to help you. A press release from Northwestern University’s Feinberg School of Medicine explains:Our hearing has a secret bodyguard: a newly discovered connection from the cochlea to the brain that warns of intense incoming noise that causes tissue damage and hearing loss, according to new research by Northwestern Medicine scientists.Scientists believe they have identified the ear’s own novel pain system that protects it from very loud or damaging noise. It may be the reason you jam your fingers in your ears when a fire engine or ambulance wails close by. The nerves that normally alert you to pain – like touching a hot burner on a stove – are not present in your inner ear. So, it needs its own private alert system.Those who suffer from hearing loss or tinnitus (ringing in the ears) may benefit from this discovery. For now, stay away from excessive noise when you feel that pain signal.Breathe deep for your brain: Nature posted a short item that will make you gasp—with a smile. When you breathe in deeply, it boosts the flow of cerebrospinal fluid in your brain. “Cerebrospinal fluid cushions the brain, flushes out waste and in rodents seems to be controlled by pulsating blood flow,” the article says. So before starting a mentally-intensive task, try taking three deep breaths and letting the air out slowly.Taste your health: Quick! Name the four tastes. Sweet, salt, sour, bitter, right? Wait: you forgot umami, the fifth one. MSG is a food additive that activates this taste. Did you know that the umami taste may benefit health? Medical Xpress says so. “Despite the widely held belief that monosodium glutamate (MSG) is an unhealthy addition to food, researchers from Tohoku University Graduate School of Dentistry, Japan, show that the taste it triggers, umami, is important for health, especially in elderly people.” A taste test with 44 elderly participants showed that loss of this sense was associated with poor health ( including low appetite and weight loss). Did you know that your gut also has umami taste sensors? This suggests that “the umami taste sensation functions in nutrient sensation and modulating digestion in the gut, which could be important for maintaining a healthy daily life.”Reset your travel clock: The body’s circadian clock has a reset button, claims a press release from Vanderbilt University. Experiments on mice, either stimulating or suppressing the neurons in the suprachiasmatic nucleus, showed promise for adjusting their daily cycles. It’s not ready for human testing, but offers hope to “lead to new treatments for conditions like seasonal affective disorder, reduce the adverse health effects of working the night shift and possibly even treat jet lag.”Unclog your arteries: The right diet can assist a ‘cleaner’ protein that is trying to protect you from blood clotting and atherosclerosis, a major cause of heart attack. Medical Xpress tells how A1M (alpha-1 microglobulin) patrols your vessels, working to “clear out oxidised heme and other harmful molecules,” converting them into harmless substances.“You could say that the tissue is rinsed by A1M in a 5-10 minute cycle, with the protein absorbing the free radicals and heme-groups. A1M acts like a bin that captures and neutralises toxic substances throughout the body – in and around all cells – that would otherwise cause inflammation and damage to surrounding tissue”, said Professor Åkerström.A1M appears to also “clean and reduce oxidised blood fats from LDL,” a primary risk factor for atherosclerosis. Some day, there may be A1M supplements; for now, help your cleaning crew by sticking to healthy dietary guidelines so that the cleaners are not overwhelmed.Fast! put out the flames: Maybe there’s something to all those Biblical admonitions about fasting. Beyond meditation and supplication, fasting appears to reduce inflammation, too. A Yale press release says the anti-inflammatory mechanism of dieting and fasting has been “revealed”.Researchers at Yale School of Medicine have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer’s disease.In their study, published in the Feb. 16 online issue of Nature Medicine, the researchers described how the compound β-hydroxybutyrate (BHB) directly inhibits NLRP3, which is part of a complex set of proteins called the inflammasome. The inflammasome drives the inflammatory response in several disorders including autoimmune diseases, type 2 diabetes, Alzheimer’s disease, atherosclerosis, and autoinflammatory disorders.Experiments on diet-regulated mice showed that BHB was able to tame the flames of the inflammasome; it probably would work for humans too. In addition to fasting, low-carb dieting and high-intensity exercise appear to have the anti-inflammatory response. The press release didn’t offer any guidelines for fasting, but it might be worth a try for better health, not that meditation and prayer are any less beneficial. New Scientist says it’s not necessary to starve to get the benefits of fasting.Stay in circulation: Walking keeps the circulatory system in good operation, but what about whose who are bedridden? They are in danger of ailments such as deep vein thrombosis, a life-threatening condition that allows clots to form. To help immobilized patients, researchers at the National University of Singapore have developed bio-inspired socks that wave like the tentacles of corals. This is better than anti-coagulant drugs, because it stimulates the body’s own protective mechanisms. “Equipped with soft actuators that mimic the tentacle movements of corals, the robotic sock emulates natural lower leg muscle contractions in the wearer’s leg, thereby promoting blood circulation throughout the wearer’s body,” the press release says. “In addition, the novel device can potentially optimise therapy sessions and enable the patient’s lower leg movements to be monitored to improve therapy outcomes.” That will be nice to know if it happens to you, but until then—if you are on your feet—give your legs a lot to do.We hope you enjoy these news clips. They are but a few samples that showcase the wonders inside your body. The Creator thought of everything. How many of these and a thousand other systems could have developed through aimless processes of chance? No; we have been blessed with dwellings for our souls that surpass the most magnificent palaces one could dream of owning. Our body palaces come equipped with billions of willing servants who know just what to do—within limits. Be a good king or queen. Treat your servants with respect and care, and they will care for you. Even in this world under the curse of sin, we have much to appreciate, enjoy, and be grateful for. And for those who love the Lord Jesus Christ, a better body awaits after this one wears out.
After a long wait, Xiaomi announced the most awaited flagship of the year – Mi 6 on April 19. Soon after the launch, the Xiaomi smartphone was made available for pre-orders for its first flash sale set for April 28. However, as of now, the handset will only be available in China. The smartphone has received over 10 lakh (1 million) pre-registration already on JD.com.The 1 million mark is based only on the number of pre-bookings on Jingdong (JD.com). However, the Chinese smartphone maker also has a tie up with a few other online retailers carrying out Mi 6 flash sale on April 28. So, if numbers are to be considered, the pre-registration number must have almost crossed 20 lakh (2 million) or even more by now. No confirmation has come on the pre-registration numbers from Xiaomi.Also Read: Xiaomi Mi 6: Full specs, price, features and everything else you need to knowXiaomi Mi 6 will be up for flash sale exclusively on JD.com, Giztop, and a few more online retail store in China on April 28. It is just another 4 days to go for the first flash sale for the Mi 6, and the pre-registration numbers are still increasing at a rapid pace. However, a previously leaked report revealed that Xiaomi will only be selling about 80,000 units approx, which means not all the users pre-registering the device will be able to get the device. This information is not confirmed by the company and the number of units may vary accordingly.As per the Chinese retail website — JD.com, the Xiaomi smartphone has already been booked by 1,108,192 consumers to be specific. The number is expected to increase, and this is because of the popularity that the smartphone started gaining ahead of its launch and also for the amazing features that it sports, especially the processor. Xiaomi Mi 6 is powered by Qualcomm’s latest octa-core Snapdragon 835 processor, which is also seen on the recently announced Samsung flagships – Galaxy S8 and S8 Plus.advertisementAlso Read: With Mi 6, Xiaomi brings iPhone 7 Plus camera technology to massesIn terms of specifications, Xiaomi Mi 6 features a 5.15-inch 1080p display and is powered by Qualcomm’s latest processor – the Snapdragon 835. Further, the smartphone comes with 6GB of RAM and is backed by a 3,350mAh battery. The Mi 6 is available in two storage variants – 64GB and 128GB. On the camera front, the smartphone features a dual camera setup at the rear with 12-megapixel wide-angle sensor, while on the front the device sports an 8-megapixel selfie snapper.As per the pricing, the Xiaomi Mi 6 comes in two variants – one with 6GB of RAM and 64GB of internal storage for CNY 2,499 (approximately Rs 23,500), while the higher-end variant with 6GB of RAM and 128GB of internal storage for CNY 2,899 (approximately Rs 27,000). There is no information on the Indian release as of yet. However, with the overwhelming response by the consumer, Xiaomi may very soon launch the Mi 6 globally. Also, the company is also rumoured to announce the Xiaomi Mi 6 Plus in the upcoming days.
TagsTransfersAbout the authorPaul VegasShare the loveHave your say Henrik Larsson linked with Southend jobby Paul Vegasa month agoSend to a friendShare the loveFormer Manchester United striker Henrik Larsson is being linked with a return to England.The Daily Mail says he has emerged as a target for Southend United.The League One side want to bring in the Swedish icon to replace Kevin Bond.The Shrimps side have been without a manager for two weeks.They remain winless this season in the league and lost 4-3 at Shrewsbury last night.They’ve lost seven and drawn one of their eight games so far this campaign.Larsson quit as Helsingborgs boss last month over the alleged level of “verbal insults” he received.
OFF TO THE POUND….A4 Audi estate car seized by police in Derry.THE police in Derry would like a quiet word with the owner of this Audi A4 car which was found abandoned on a bad bend and blocking a farmer’s property.PSNI Foyle say on its Facebook page: “Could the owner of this Audi A4 estate which was left for a considerable period of time on the Beragh Hill Road, make contact with Constable Brogan of Ballyarnett NPT at Strand Road PSNI Station ASAP.“We would like to know why it was parked blocking a farmers property, was on a bad bend, had a number of dodgy tyres, was full of empty tins of alcohol and had a bong in the rear seat. “It’s also showing no insurance and was found on a public road.“We have seized it for now and happy to discuss it with the owner if located.“Police checks regarding the owner have been inconclusive thus far.”POLICE KEEN TO TRACE ‘INCONSIDERATE’ OWNER OF THIS ABANDONED AUDI CAR was last modified: January 6th, 2018 by John2John2 Tags: ShareTweet BERAGH HILL ROADCONSTABLE BROGANPOLICE KEEN TO TRACE ‘INCONSIDERATE’ OWNER OF THIS ABANDONED AUDI CARPSNI FOYLE
Related StoriesNanotechnology-based compound used to deliver hepatitis B vaccineResearchers discover gene linked to healthy aging in wormsResearchers identify gene mutations linked to leukemia in children with Down’s syndromeAt present, there is no curative treatment for AS, so all males with X-linked disease and all males and females with ARAS, as well as a certain percentage of patients with ADAS, will ultimately show progression to ESKD. The only recommended treatment nowadays for this disease is RAAS (renin-angiotensin-aldosterone system) blockade. Currently RAAS is being tested in children even before the onset of proteinuria.Currently there is an ongoing trial using bardoxolone and another using anti miRNA21 is expected to start soon. Other drugs under study for AS are paricalcitol, lipid-lowering agents, epidermal growth factor receptor inhibitors, chaperones, stem-cell based therapies, inhibitors of STAT3, etc.”A specific disease-modifying therapy for AS remains an unmet need, but I am sure this will change, because AS has become a very attractive disease for pharmaceutical companies to target”, emphasizes Professor Torra and gives five reasons:(1) it is an excellent model of chronic kidney disease (CKD) with proteinuria and fibrosis that may be extrapolated to other more common causes of CKD;(2) any drug approved for this disease will have an orphan drug designation with its consequent benefits, such as shortened approval timeline, financial incentives, and a period of market exclusivity;(3) the number of patients to be treated will be substantial, AS being the second more frequent inherited kidney disease after ADPKD;(4) patients are young and have very few comorbidities, which facilitates clinical trials;(5) there is no approved treatment for ASSource:ERA-EDTAJournal reference:Torra, R & Furlano, M. (2019) New therapeutic options for Alport syndrome. Nephrology Dialysis Transplantation. https://doi.org/10.1093/ndt/gfz131. But similarly to other renal diseases, this is probably too late an endpoint to make a significant impact on the course of the disease. Theoretically, treatment prior to the appearance of renal fibrosis offers more promising long-term renal outcomes. GBM aspect and degree of fibrosis on renal biopsy as well as proteinuria could be excellent endpoints for clinical trials.”Professor Roser Torra, Barcelona/Spain, main author of the review published in NDT today Reviewed by Kate Anderton, B.Sc. (Editor)Jun 13 2019Alport syndrome (AS) is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure. Depending on the mutated gene and the pattern of inheritance, there are three types of AS. Mutations in COL4A5 cause severe disease in males and a disease of variable severity (but usually much less severe) in females. Mutations in COL4A3 and COL4A4 are the cause of the autosomal forms of AS. Homozygous or compound heterozygous mutations in COL4A3 or COL4A4 are the cause of autosomal recessive AS (ARAS), while a single mutation in either of these genes causes autosomal dominant AS (ADAS).Having only one mutation in COL4A3 or COL4A4 can cause a phenotype that ranges from nothing (i.e. some parents of children with ARAS) to haematuria alone or to proteinuria and subsequent renal failure on top of haematuria. Over the past several years it has become increasingly apparent that more patients reach end-stage kidney disease (ESKD) due to ADAS than due to classical X-linked AS or ARAS, even though this progression occurs at a much older age. The seminal determinant of disease progression in AS logically seems to be the amount of damage in the glomerular basement membrane (GBM).A surrogate pathological marker may be tubulointerstitial fibrosis, which has been recognized as the key feature in progressive renal damage leading to ESKD. The glomerular disease and the podocyte stress response lead to the secretion and distribution of profibrotic chemokines and cytokines, which are the main causes of interstitial fibrosis and tubular atrophy. Progression from haematuria to microalbuminuria and progression from microalbuminuria to overt proteinuria represent very important steps in the course of AS. As for many renal diseases, the primary endpoint for AS clinical trials is or will be the decline in GFR.
COMMENTS COMMENT April 16, 2019 Published on Electoral politics in Bengaluru — the tech city that contributes around $50 billion or 40 per cent of India’s total IT exports — is increasingly being shaped by citizen activism.The city has three urban Parliamentary constituencies — Bangalore North, Bangalore Central, Bangalore South, and one semi-urban constituency — Bangalore Rural.In the last two decades, citizen activism has percolated to all levels of political discourse and governance, be it the civic body (BBMP), the State Assembly or Parliament.The large-scale migration experienced by the city in the last two decades has led to the crumbling of civic infrastructure. The citizens’ involvement has changed electoral politics in the city with numerous agitations — ‘Steel Bridge Beda’, ‘Circular Railu Beku’, ‘Footpath Beku’, ‘Save Trees’, ‘Save Lakes’, especially the Bellandur lake.The organisations heading the activism are ‘Whitefield Rising’ and ‘Citizens for Bengaluru’ which have taken the discourse from social media to the streets. In fact, the previous government scrapped the steel flyover proposal just before the Assembly elections.‘A positive effect’In the absence of vote-bank politics in the city, the Resident Welfare Association (RWA) is playing a pivotal role in the formulation or shaping public policies, especially garbage clearance, traffic regulation and regulation of commercial spaces in residential layouts. Rekha Chari, former president, Malleswaram Swabhimana Initiative (MSI) said, “Citizen activism in Bengaluru is on the rise and impacting the city in a positive way. We interact regularly with our elected representatives, be it the MLA, corporator or MPs, to get our problems solved.“We had come out with a citizen manifesto during the Assembly election and, today, many parties and candidates have included points from that,” she added. Candidates now are relying on the performance and popularity of local corporators and MLAs. In the 2018 Assembly election, the city witnessed a shift of urban votes to the Congress, which has worried the BJP. SHARE SHARE SHARE EMAIL state politics Bengaluru
Published on NBFC July 10, 2019 Press Trust of India Bengali film actor Rituparna Sengupta has been summoned by the Enforcement Directorate next week in connection with the investigation into the Rose Valley ponzi scam, a day after it summoned superstar Prosenjit Chatterjee in the same case. According to the sources, Sengupta allegedly accompanied Rose Valley group chairman Gautam Kundu on several foreign trips and helped him in the sale and production of films. “We have summoned actor Rituparna Sengupta in connection with the Rose Valley scam. She has been asked to appear next week,” ED sources told PTI. Phone calls made to Sengupta for her reaction went unanswered. Chatterjee, meanwhile, had been asked to depose before the ED officials at the CGO Complex office in Salt Lake on July 19. The Tollywood actor’s statement will be recorded under the Prevention of Money Laundering Act (PMLA). The sources said the agency wanted to question Chatterjee about ₹2.75 crore received by his company, Idea Locations and Production Pvt Ltd, from the Rose Valley group between 2010 and 2011. Of this, Chatterjee is suspected to have received about ₹23.5 lakh. The probe agency wants to understand the purpose of these funds, they claimed. Chatterjee has acted in several films produced and distributed by Rose Valley, notable among them being Moner Manush and Hangover. A probe by the agency has revealed that Rose Valley, on paper, undervalued the film’s production cost and used depositors’ money to fund Hangover, the ED sources added. The ED had on Monday interrogated senior Trinamool Congress leader Madan Mitra in connection with the ponzi scam. SHARE COMMENT West Bengal SHARE SHARE EMAIL economic offence COMMENTS