TagsTransfersAbout the authorPaul VegasShare the loveHave your say Chelsea attacker Willian wanted by Juventusby Paul Vegasa month agoSend to a friendShare the loveChelsea attacker Willian is wanted by Juventus.The Telegraph say the Turin club intends to move for the Brazilian next summer, when his contract with the Londoners expires.Willian’s agreement with Chelsea expires in the summer of 2020 – and so far negotiations for its extension have not been successful .The 31-year-old striker moved to Chelsea in 2013 from Anzhi. During his time with Chelsea, Willian has played 203 matches in the Premier League and scored 28 goals.
Some $13 million has been set aside in the 2013/14 Estimates of Expenditure, now before the House of Representatives, to continue work on the Water Resources Authority’s (WRA) Evaluating Groundwater Recharge in the Upper Rio Cobre Basin programme. The project seeks to assess the potential for water-related developments and the resource capacity to meet present and future demand, as well as the continuous updating of the National Water Resources Master Plan. The allocation for this fiscal year will go towards: providing additional training to other WRA staff members in the application of isotopes techniques in hydrology and the procurement of two battery operated pumps. The funds will also go towards the development of a database with new and existing information pertaining to the recharging of groundwater in the Rio Cobre, consisting of data and groundwater levels, spring and river discharge, isotopes, chemistry and meteorological parameters. Achievements up to February this year include: procurement of current meters and groundwater probes with rainwater collectors; conceptual model of groundwater recharge and flow in the Rio Cobre hydro geological system developed; training of WRA staff in the application of isotopes techniques in hydrology; first set of samples collected and sent to a laboratory in Austria for isotope analysis. The project, which is being administered through the Ministry of Water, Land, Environment and Climate Change, began in April 2012, and is slated to end in March 2014. By Chris Patterson, JIS Reporter
NEW DELHI: The Rajasthan government on Friday said it will re-examine the Pehlu Khan case, in which a district court acquitted the six men accused of thrashing the dairy farmer on suspicion of cattle smuggling two years ago. Pehlu Khan, whose beating was captured on a mobile phone video used by Rajasthan police to identify his attackers, died of his injuries three days later. The state government will set up a Special Investigation Team or SIT that will look at police lapses in the investigation. In explaining its judgement, the Alwar district court, which gave the accused the benefit of doubt, highlighted the fact they had not been named in Pehlu Khan’s statement; the names were added two years later. The court also pointed out that an identification parade had not been held.
OTTAWA – Foreign Affairs Minister Chrystia Freeland is hosting a pair of Mexican dignitaries who will hold key cabinet portfolios once their country’s incoming government take power.Freeland and International Trade Minister Jim Carr will sit down for bilateral meetings in Ottawa today with Mexico’s future foreign affairs minister Marcelo Ebrard and economy minister Graciela Marquez. The meetings come just a few weeks after Canada, Mexico and the United States agreed to an updated North American free trade pact.The agreement narrowly beat a deadline imposed by the U.S. Congress to get the deal fast-tracked and voted on by Dec. 1, ahead of Mexican president-elect Andres Manuel Lopez Obrador’s incoming government.The visiting Mexican officials, Ebrard and Marquez, will take on their ministerial roles once Lopez Obrador’s government takes office.Canada and Mexico are still dealing with stinging steel and aluminum tariffs imposed by the Trump administration _ and both countries have responded by slapping the U.S. with retaliatory duties of their own.
As Chair of The Elders, Kofi Annan has released a New Year’s message on behalf of The Elders.He reflects on the events of 2014 and looks towards 2015, saying: “Today more than ever, we need far-sighted leaders who can see beyond their national boundaries and beyond the next election.”“When Nelson Mandela founded The Elders in 2007, he urged us to “support courage where there is fear”. Looking back at the events of 2014 and ahead to the global challenges we confront in 2015, it can seem that our world is almost paralysed by fear,” writes Annan. “There are those for whom fear is a daily reality – people who fear for their lives and those of their loved ones; people who face the constant threat of violence, disease, or hunger.“But there are also fears that have less basis in fact – fear of change, fear of the unknown, fear of ‘the other.’ Often irrational, these fears can lead us to retreat behind barricades, turn our backs on those in need, and persecute those we see as a threat. We see this in our reluctance to give shelter to those who flee violent conflict; in the rise of aggressive nationalism and identity politics; and in growing religious extremism and sectarianism.Far-sighted leaders“And then there are the fears we all too often see in our political leaders – the fear of losing face, of losing popularity, of losing power. These concerns may seem trivial, but when our leaders are in the grip of such fears, the prospects for our world are dire indeed.“All too frequently, leaders will concern themselves with matters that are closest at hand, while the most serious issues are often more distant –geographically or in time. For example, if we fail to tackle climate change the worst effects will be suffered by future generations and by poor countries far from global power centres. And I have to ask whether we would still be struggling to find effective treatment and vaccines for Ebola if it had been a problem in the cities of Europe or North America rather than in Africa.“Today more than ever, we need far-sighted leaders who can see beyond their national boundaries and beyond the next election.“Looking back at the world’s most distinguished and respected leaders, it was never their ability to deliver tax cuts, impose strict immigration policies, or launch acts of armed aggression on other countries that earned our admiration. It was their wisdom, their integrity and their compassion for their fellow human beings.A unique position“As Elders, we understand the constraints that can inhibit our political leaders. Several of my fellow Elders have held political office at the highest levels and are well aware of the pressures that leaders can face. This understanding, coupled with the freedom of no longer being in office, puts us in a unique position to support and encourage today’s leaders to take the courageous decisions the world desperately needs.“For example, in the past year, we have travelled to Iran and Myanmar to offer whatever help we can as these countries’ leaders take the often precarious path towards reform, greater openness, and ultimately, a more peaceful existence. The Elders have also spoken out about the need for governments to provide greater protection for women and girls, and take a stand against the violence, discrimination and oppression they suffer in many societies.Shared vision“2015 will be a crucial year in the battle to avert a climate change catastrophe, and in the run-up to December’s Paris summit, we will be supporting efforts to secure a bold new binding agreement to cap carbon emissions. We are calling for an equitable agreement under which the world’s richer countries support the aspirations of other nations to follow a sustainable development path. Such an agreement is clearly in the interests of our entire planet but it will require far-sighted courageous action on the part of our political leaders.“They would do well to recall the words of Franklin D Roosevelt in his inaugural address as US President in 1933: “the only thing we have to fear is fear itself — nameless, unreasoning, unjustified terror which parlayzes needed efforts to convert retreat into advance.”“But Roosevelt went on to say that courageous leadership requires the understanding and support of the people. We need to make clear to our leaders what we expect of them; we need to hold them to account; but we also need to let them know that if they have the courage to do the right thing, then we will support them. We need to help them overcome their fear; share their burden; and be willing to pay the price of progress.“For progress rarely comes without a price: social change means being prepared to share; a just and ordered society means accepting constraints on our behaviour; and making peace with our enemies means being open to compromise and forgiveness.Progress means participation“As we begin another new year, I am confident that it will be the power and willingness of ordinary citizens – especially young people – to catalyse positive change and support courageous, compassionate leadership that will make a difference. Everyone can play their part – whether it is through participation in democratic processes, through peaceful protest against injustice, through harnessing the power of social media and new modes of communication, or simply through offering support and solidarity to those in need.“This is where my greatest hopes lie for 2015. On behalf of all the Elders, I wish you a happy, healthy and peaceful year.”
Milya Timergaleyeva, VP, market strategy, Oregan Networks talks about the challenges facing pay TV operators in delivering advanced services.What are the main challenges facing pay TV service providers as they attempt to upgrade their subscriber bases to receive advanced connected or hybrid TV services?The biggest common challenge faced by MSOs is meeting the growing demand for bandwidth, as content consumption preferences shift toward non-linear models. Intensified by the increasing appetite for Full HD and 4K content, the ‘bandwidth bottleneck’ has the potential to stress both managed and Over the Top Services to a level where customer experience can be adversely impacted.DRM fragmentation also continues to raise challenges for operators that deploy services across multiple devices and networks, and this is an area where goalposts are constantly changing, in terms of new security requirements from studios on UHD content, as well as ecosystem changes such as those recently made by Google to the Chrome browser.As a platform and services vendor, Oregan employs a combination of well-established technology building blocks and innovation components that tackle these issues. During IBC this year, Oregan will showcase recent integration with the V-Nova Perseus compression technology which holds a promise of significantly reducing the bandwidth requirements, thus making premium content accessible at lower OPEX levels. Core to Oregan’s bandwidth solutions strategy is close alignment and pre-integration with leading CDN and DVR vendors, such as Alcatel Lucent.Thirdly, the high velocity of the evolution of standards and emerging connectivity use cases pose operational challenges for operators who wish to stay relevant and competitive. On the one hand, the in-sourcing platform management strategies have proven effective for larger operators, on the other hand, the need to continuously explore, implement and trial new products in an Agile manner, have created an elevated demand for highly skilled engineering teams and product evolution methodologies that can be ‘plugged’ into a project rapidly and deliver to a high standard.How useful is cloud technology in helping deliver advanced TV services to pay TV operators’ subscribers and which applications are likely to be prioritized by operators?The trend to virtualize services that were once provided exclusively within the operator’s own managed headend is well underway. During the last 12 months Oregan has worked on deployment projects where many aspects of the traditional headend have been moved out into the cloud, allowing operators to reduce complexity and costs associated with onsite hosting.We are involved in projects today with tier-1 telecoms operators, where key video delivery platform components such as the CMS, Network PVR, DRM Key Server, TR-069 ACS Server and Upgrade Management Server are all provided as managed services hosted in the Cloud.Indeed, we see traditional cable and satellite operators deploying on-demand VOD services in some markets, where the Service Delivery Platforms I entirely outsourced and hosted in the cloud. This enables rapid time to market as well as immediate economies of scale, by utilizing pre-established cloud encoding and CDN platforms for OTT delivery to hybrid STBs and other OTT devices.Oregan’s video client technology has been developed from the outset to bring together the worlds of traditional broadcast, with IPTV and OTT technologies. A legacy or new generation STB running Oregan’s middleware can mix-and-match content from broadcast, IPTV and OTT sources, whilst providing a seamless and unified user experience to the consumer. The latest iterations of Oregan’s Secure Media Player solution, brings this consistency to multi-screen devices and OTT platforms, as well as the more established traditional CPE.What are the main challenges facing pay TV service providers as they attempt to upgrade their subscriber bases to receive advanced connected or hybrid TV services?The first and foremost decision faced by an operator is the approach to the existing devices. The reality is that the initial investment that was made deploying the original CPE is frequently making it difficult to commercially justify a complete replacement. Oregan’s legacy Pay TV migration methodology encapsulates the key product evolution process that allows the operator to synchronize, wherever possible, the capabilities and features across legacy and new generation devices.Oregan’s project experience with BT and its legacy Mediaroom STBs enables us to offer a field-proven solution to operators where the in-field upgrade process is flawless, with the entire fleet of devices upgraded remotely, courtesy of a well designed and implemented remote upgrade methodology. The crucial goal and a measure of success of any such upgrade project is elimination of any need for ‘truck rolls’. As part of the initial technical and financial analysis, Oregan carries out a thorough impartial feasibility assessment, which will determine the optimal product evolution path, feature sets, content security implications, timescales and any trade-offs related to the legacy STB’s intrinsic capabilities.What are the principal technology choices facing operators as they seek to build next-generation TV platforms and what are the key advantages and disadvantages of each?As technology sourcing becomes increasingly modular, with emphasis on upgradability and future-proofness, the component choices are becoming less restrictive. In this new scenario, which is made possible by the general move towards open architectures and community-sourced components, the choices tend to be related to the operating system utilized inside the CPE, the degree of association and prominence of competing OTT services offered side-by-side with the core content offering and, thirdly, the content protection technologies.A continued exploitation of multicast delivery infrastructure for live events, especially sporting events is an option that many operators are having to determine their approach to.And lastly, offering support for Common Encryption standards across devices, which enables operators to simplify the head-end infrastructure of a multi-DRM deployment is a transition that many operators consider as a matter of natural platform evolution.Oregan Networks provides market-leading technology expertise in delivery of Digital TV over broadcast and IP networks, with emphasis on ensuring content security, quality of service for consumers and mitigating project risk. To schedule a discussion with Oregan at IBC, email email@example.com.
Reviewed by James Ives, M.Psych. (Editor)Mar 22 2019The increase in cesarean sections is on the verge of a global epidemic. Though the World Health Organization recommends an optimal C-section rate of 10-15 percent, the United States’ C-section rate is more than 30 percent.In many Latin American countries, the procedure is sky rocketing, reaching more than 50 percent in some.While C-sections are lifesaving in some cases, they are increasing beyond recommended rates with harmful consequences for children’s health.Cesarean delivered children tend to be susceptible to infections, obesity, asthma and allergies. This occurs in part because many mothers are unable to successfully breastfeed them after a C-section.However, recent research shows that this may be culturally mediated. In some parts of the world, mothers are able to breastfeed successfully after C-section deliveries, and this practice may reduce their negative child health effects.Amanda Veile, an assistant professor of anthropology at Purdue University, and her team report that indigenous mothers in farming communities in Yucatán, Mexico, breastfeed for about 1.5 months longer following cesarean deliveries than they do following vaginal deliveries. Veile believes this is possible because the mothers live in an exceptionally supportive breastfeeding environment.”Moms living in this Mexican community don’t have to hide in a bathroom to feed their child when they are in public,” says Veile, a biological anthropologist who specializes in infant and child development. “Here, it is a cultural norm to breastfeed anytime, anywhere, and to sustain breastfeeding for longer than two years. And we think that prolonged breastfeeding offers protective benefits that reduces some of the health problems we often see in children delivered by C-section.”Veile’s research appears in the American Journal of Human Biology’s special issue on the evolutionary and biocultural causes and consequences of rising cesarean delivery rates. Veile and collaborator Karen Rosenberg, a professor from the University of Delaware, are the guest editors for the special issue. It features 10 research articles written by anthropologists, biologists and healthcare practitioners, which are available open access through spring 2019.Related StoriesBreastmilk antibody necessary to prevent necrotizing enterocolitis in preterm infantsMothers can transfer life-long protection against infection to infants by breastfeedingPre-pregnancy maternal obesity may affect growth of breastfeeding infantsIn Veile’s study, she and her team compared breastfeeding durations and childhood infection rates based on how the child was born to Yucatec Maya farmers. Following 88 children from birth until age 5, the results show that those children born via C-sections were breastfed for about 2.7 years, whereas vaginally delivered children were breastfed for just over 2.5 years. There was no difference in infection rates between the two groups of children.”What a powerful message supporting breastfeeding,” Veile says. “We need to continue studying this issue, but it seems that these mothers, perhaps subconsciously, increased their breastfeeding efforts post-cesarean.”Veile says that Yucatec Maya women do experience post-cesarean challenges in the hospital environment, such as prolonged separation from their infants, latching issues and delayed milk let-down reflex. Still mothers overcome these challenges through determination, consumption of special foods, and the use of herbs and compresses. They also receive emotional support and breastfeeding advice from their family and friends.”Now that C-sections are becoming more universal, it is important to understand more about the consequences for children’s health in a variety of settings,” Veile said. “This includes very rural communities worldwide that are transitioning to increased health care access, while simultaneously experiencing poor community sanitation and the double burden of malnutrition.” Source:https://www.purdue.edu/newsroom/releases/2019/Q1/c-sections-are-seen-as-breastfeeding-barrier-in-the-u.s.,-but-not-in-other-global-communities.html
Related StoriesNanotechnology-based compound used to deliver hepatitis B vaccineResearchers discover gene linked to healthy aging in wormsResearchers identify gene mutations linked to leukemia in children with Down’s syndromeAt present, there is no curative treatment for AS, so all males with X-linked disease and all males and females with ARAS, as well as a certain percentage of patients with ADAS, will ultimately show progression to ESKD. The only recommended treatment nowadays for this disease is RAAS (renin-angiotensin-aldosterone system) blockade. Currently RAAS is being tested in children even before the onset of proteinuria.Currently there is an ongoing trial using bardoxolone and another using anti miRNA21 is expected to start soon. Other drugs under study for AS are paricalcitol, lipid-lowering agents, epidermal growth factor receptor inhibitors, chaperones, stem-cell based therapies, inhibitors of STAT3, etc.”A specific disease-modifying therapy for AS remains an unmet need, but I am sure this will change, because AS has become a very attractive disease for pharmaceutical companies to target”, emphasizes Professor Torra and gives five reasons:(1) it is an excellent model of chronic kidney disease (CKD) with proteinuria and fibrosis that may be extrapolated to other more common causes of CKD;(2) any drug approved for this disease will have an orphan drug designation with its consequent benefits, such as shortened approval timeline, financial incentives, and a period of market exclusivity;(3) the number of patients to be treated will be substantial, AS being the second more frequent inherited kidney disease after ADPKD;(4) patients are young and have very few comorbidities, which facilitates clinical trials;(5) there is no approved treatment for ASSource:ERA-EDTAJournal reference:Torra, R & Furlano, M. (2019) New therapeutic options for Alport syndrome. Nephrology Dialysis Transplantation. https://doi.org/10.1093/ndt/gfz131. But similarly to other renal diseases, this is probably too late an endpoint to make a significant impact on the course of the disease. Theoretically, treatment prior to the appearance of renal fibrosis offers more promising long-term renal outcomes. GBM aspect and degree of fibrosis on renal biopsy as well as proteinuria could be excellent endpoints for clinical trials.”Professor Roser Torra, Barcelona/Spain, main author of the review published in NDT today Reviewed by Kate Anderton, B.Sc. (Editor)Jun 13 2019Alport syndrome (AS) is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure. Depending on the mutated gene and the pattern of inheritance, there are three types of AS. Mutations in COL4A5 cause severe disease in males and a disease of variable severity (but usually much less severe) in females. Mutations in COL4A3 and COL4A4 are the cause of the autosomal forms of AS. Homozygous or compound heterozygous mutations in COL4A3 or COL4A4 are the cause of autosomal recessive AS (ARAS), while a single mutation in either of these genes causes autosomal dominant AS (ADAS).Having only one mutation in COL4A3 or COL4A4 can cause a phenotype that ranges from nothing (i.e. some parents of children with ARAS) to haematuria alone or to proteinuria and subsequent renal failure on top of haematuria. Over the past several years it has become increasingly apparent that more patients reach end-stage kidney disease (ESKD) due to ADAS than due to classical X-linked AS or ARAS, even though this progression occurs at a much older age. The seminal determinant of disease progression in AS logically seems to be the amount of damage in the glomerular basement membrane (GBM).A surrogate pathological marker may be tubulointerstitial fibrosis, which has been recognized as the key feature in progressive renal damage leading to ESKD. The glomerular disease and the podocyte stress response lead to the secretion and distribution of profibrotic chemokines and cytokines, which are the main causes of interstitial fibrosis and tubular atrophy. Progression from haematuria to microalbuminuria and progression from microalbuminuria to overt proteinuria represent very important steps in the course of AS. As for many renal diseases, the primary endpoint for AS clinical trials is or will be the decline in GFR.
politics Rahul Gandhi RELATED Focus will be on unemployment, job creation: Rahul SHARE SHARE EMAIL Published on COMMENT national elections SHARE Congress chief Rahul Gandhi on Thursday vowed to set up a separate ministry for fishermen if the Congress is voted to power in the Lok Sabha elections, saying unlike Prime Minister Narendra Modi he did not make “fake promises”.He was addressing the National Fishermen Parliament organised by All India Fishermen Congress in Thriprayar near here.“My commitment to you is that the moment we win the 2019 elections, all the fishermen of the country will get their own dedicated ministry in Delhi,” Rahul Gandhi said. Assuring the fishermen that he would fulfil the promise if the Congress wins, the Congress chief said, “I am not like Narendra Modi. I don’t make fake promises.” “Please look at my speeches. When I say something, I only say it because I have decided to do it,” he said. Rahul Gandhi. File photo – PTI March 14, 2019 COMMENTS
Nirmohi Akhara, one of the litigants in the Ayodhya case, on Tuesday moved the Supreme Court opposing the Centre’s plea seeking return of 67.390 acre of “non-disputed” acquired land around the disputed Ram Janambhoomi-Babri Masjid site to original owners.The Allahabad High Court in 2010 had decided that 2.77-acre disputed land at Ram Janambhoomi-Babri Masjid site would be divided into three equal parts and will be handed over to — Nirmohi Akhara, Sunni Waqf Board, and Ram Lalla.Also read: Centre seeks SC’s permission to return land around disputed Ayodhya siteThe Nirmohi Akhara, in its fresh plea, has opposed the Centre’s application by which it had sought modification of the Supreme Court’s 2003 order to allow it to return to original owners the 67.390 acre of “non-disputed” acquired land around the disputed Ram Janambhoomi-Babri Masjid site in Ayodhya.The application has said that the Centre has proposed returning of acquired land to Ram Janambhoomi Nyas and that there are many temples on the acquired land and their rights would be affected if the land is returned to one party.The apex court had recently appointed mediators to find an amicable solution to the vexatious land dispute. Supreme Court forms 3-member team to resolve Ayodhya dispute Supreme Court of India COMMENT SHARE Ayodhya April 09, 2019 RELATED Chronology of Ayodhya land dispute case Published on SHARE SHARE EMAIL COMMENTS